Checks for coeliac disease by detecting immune response to gluten.

When Levels are High

Positive result suggests possible coeliac disease, requiring further confirmation with biopsy.

When Levels are Low

Low total IgA may mean an alternative test is needed.

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Understanding trends in the results

It doesn't usually need to be repeated.  But, a declining TTG level after diagnosis suggests good adherence to a gluten-free diet; persistent elevation may mean ongoing gluten exposure.

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